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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-5-22
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pubmed:abstractText |
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is lost as a function of prostate tumor androgen dependence. While the transcriptional activity of the androgen receptor (AR) is inhibited by PTEN in androgen sensitive prostate cancer (CaP), the role of PTEN in androgen disease is unclear.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androgen Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Androgen Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Androgens,
http://linkedlifedata.com/resource/pubmed/chemical/Anilides,
http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline,
http://linkedlifedata.com/resource/pubmed/chemical/Nitriles,
http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Protein v-akt,
http://linkedlifedata.com/resource/pubmed/chemical/PTEN Phosphohydrolase,
http://linkedlifedata.com/resource/pubmed/chemical/PTEN protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Prostate-Specific Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Androgen,
http://linkedlifedata.com/resource/pubmed/chemical/Tosyl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53,
http://linkedlifedata.com/resource/pubmed/chemical/bicalutamide
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2005 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1114-23
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16637073-Androgen Antagonists,
pubmed-meshheading:16637073-Androgen Receptor Antagonists,
pubmed-meshheading:16637073-Androgens,
pubmed-meshheading:16637073-Anilides,
pubmed-meshheading:16637073-Blotting, Western,
pubmed-meshheading:16637073-Cell Cycle,
pubmed-meshheading:16637073-Cell Line, Tumor,
pubmed-meshheading:16637073-Cell Proliferation,
pubmed-meshheading:16637073-Doxycycline,
pubmed-meshheading:16637073-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16637073-Genes, Tumor Suppressor,
pubmed-meshheading:16637073-Humans,
pubmed-meshheading:16637073-Male,
pubmed-meshheading:16637073-Neoplasms, Hormone-Dependent,
pubmed-meshheading:16637073-Nitriles,
pubmed-meshheading:16637073-Oncogene Protein v-akt,
pubmed-meshheading:16637073-PTEN Phosphohydrolase,
pubmed-meshheading:16637073-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:16637073-Promoter Regions, Genetic,
pubmed-meshheading:16637073-Prostate-Specific Antigen,
pubmed-meshheading:16637073-Prostatic Neoplasms,
pubmed-meshheading:16637073-Receptors, Androgen,
pubmed-meshheading:16637073-Signal Transduction,
pubmed-meshheading:16637073-Tosyl Compounds,
pubmed-meshheading:16637073-Transfection,
pubmed-meshheading:16637073-Tumor Suppressor Protein p53
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pubmed:year |
2006
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pubmed:articleTitle |
Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells.
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pubmed:affiliation |
Department of Molecular Physiology and Biological Physics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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