|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2006-4-25
|
|
pubmed:abstractText |
RECS1 is a mechanical stress responsive gene and RECS1 knockout (KO) mice (older than 14 months) are prone to cystic medial degeneration (CMD). The present study was designed to assess whether RECS1 KO mice have altered gelatinase (matrix metalloproteinase (MMP)-2 and MMP-9) levels and whether they are prone to aortic dilation.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1346-9843
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
70
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
615-24
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16636500-Aging,
pubmed-meshheading:16636500-Animals,
pubmed-meshheading:16636500-Aorta,
pubmed-meshheading:16636500-Matrix Metalloproteinase 2,
pubmed-meshheading:16636500-Matrix Metalloproteinase 9,
pubmed-meshheading:16636500-Matrix Metalloproteinases,
pubmed-meshheading:16636500-Membrane Proteins,
pubmed-meshheading:16636500-Mice,
pubmed-meshheading:16636500-Mice, Knockout,
pubmed-meshheading:16636500-Myocytes, Smooth Muscle,
pubmed-meshheading:16636500-Stress, Mechanical,
pubmed-meshheading:16636500-Vasodilation
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
RECS1 is a negative regulator of matrix metalloproteinase-9 production and aged RECS1 knockout mice are prone to aortic dilation.
|
|
pubmed:affiliation |
Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
