| pubmed-article:16635577 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0006644 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0037390 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0234621 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C1655730 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C1705491 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0338207 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C0205265 | lld:lifeskim |
| pubmed-article:16635577 | lifeskim:mentions | umls-concept:C1555582 | lld:lifeskim |
| pubmed-article:16635577 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16635577 | pubmed:dateCreated | 2006-7-24 | lld:pubmed |
| pubmed-article:16635577 | pubmed:abstractText | Localized changes in oxygen consumption related to increased neural activity can result in a small and transient "initial dip" of the blood oxygenation level-dependent (BOLD) signal used in functional magnetic resonance imaging (fMRI). The initial dip has been of great interest to the fMRI community because it may provide a more accurate and localized measure of neural activity than the conventional BOLD signal increase. Although potentially useful as a technique for human brain mapping, the initial dip is not always detected and has been a source of some controversy. In this study, the BOLD response to a 4-s long visual stimulus was measured with a 3-T MRI system in 5 healthy volunteers both before and immediately after a 200-mg oral caffeine dose. The caffeine dose significantly (P < 0.001) reduced or eliminated the initial dip in all subjects. These findings suggest that caffeine usage may be a key factor in the detection of the initial dip in human fMRI studies. | lld:pubmed |
| pubmed-article:16635577 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16635577 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16635577 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16635577 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16635577 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16635577 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16635577 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16635577 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16635577 | pubmed:issn | 1053-8119 | lld:pubmed |
| pubmed-article:16635577 | pubmed:author | pubmed-author:LiuThomas TTT | lld:pubmed |
| pubmed-article:16635577 | pubmed:author | pubmed-author:BehzadiYashar... | lld:pubmed |
| pubmed-article:16635577 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16635577 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:16635577 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:16635577 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16635577 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16635577 | pubmed:pagination | 9-15 | lld:pubmed |
| pubmed-article:16635577 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:meshHeading | pubmed-meshheading:16635577... | lld:pubmed |
| pubmed-article:16635577 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16635577 | pubmed:articleTitle | Caffeine reduces the initial dip in the visual BOLD response at 3 T. | lld:pubmed |
| pubmed-article:16635577 | pubmed:affiliation | Center for Functional Magnetic Resonance Imaging and Department of Radiology, University of California-San Diego, 9500 Gilman Drive, La Jolla, MC 0677, CA 92093-0677, USA. | lld:pubmed |
| pubmed-article:16635577 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16635577 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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