Source:http://linkedlifedata.com/resource/pubmed/id/16635174
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-4-25
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pubmed:abstractText |
In treating pediatric patients with systemic lupus erythematosus (SLE), it is necessary to quickly attain remission to avoid sequelae in various organs and to maintain it over a long period. However, to maintain remission, the prolonged use of immunosuppressants which have various adverse effects, is often necessary in addition to steroids, and complications due to such immunosuppressants pose very important problems. A regimen of mizoribin (MZR) at 150 mg/day divided into two or three doses has been recommended, but while this regimen has been safe, its efficacy has not been satisfactory. However, MZR produces effects dose-dependently, and the dose recommended to date may have been insufficient for the treatment of children with SLE.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1328-8067
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
152-7
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pubmed:dateRevised |
2008-5-21
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pubmed:meshHeading |
pubmed-meshheading:16635174-Adolescent,
pubmed-meshheading:16635174-Child,
pubmed-meshheading:16635174-Female,
pubmed-meshheading:16635174-Humans,
pubmed-meshheading:16635174-Immunosuppressive Agents,
pubmed-meshheading:16635174-Lupus Erythematosus, Systemic,
pubmed-meshheading:16635174-Male,
pubmed-meshheading:16635174-Ribonucleosides,
pubmed-meshheading:16635174-Uric Acid
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pubmed:year |
2006
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pubmed:articleTitle |
High-dose mizoribine treatment for adolescents with systemic lupus erythematosus.
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pubmed:affiliation |
Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan. nozu@med.kobe-u.ac.jp
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pubmed:publicationType |
Journal Article,
Case Reports
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