rdf:type |
|
lifeskim:mentions |
umls-concept:C0001721,
umls-concept:C0001962,
umls-concept:C0017262,
umls-concept:C0025921,
umls-concept:C0025923,
umls-concept:C0026809,
umls-concept:C0076829,
umls-concept:C0185117,
umls-concept:C0815102,
umls-concept:C1260899,
umls-concept:C1335641,
umls-concept:C1416894,
umls-concept:C1706158,
umls-concept:C1706701,
umls-concept:C2911684
|
pubmed:issue |
5
|
pubmed:dateCreated |
2006-4-25
|
pubmed:abstractText |
Topiramate, an anticonvulsant, has been reported to increase the number of abstinent days and decrease craving in alcohol-dependent individuals. However, the neurobiological basis for topiramate's effect is unknown. To assess topiramate's effect on ethanol's rewarding and conditioning rewarding effects, the present experiments examined the effects of topiramate on the acquisition and expression of ethanol-induced conditioned place preference (CPP) in DBA/2J and C57BL/6J mice.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0145-6008
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
783-90
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:16634846-Alcoholism,
pubmed-meshheading:16634846-Animals,
pubmed-meshheading:16634846-Anticonvulsants,
pubmed-meshheading:16634846-Conditioning (Psychology),
pubmed-meshheading:16634846-Ethanol,
pubmed-meshheading:16634846-Fructose,
pubmed-meshheading:16634846-Male,
pubmed-meshheading:16634846-Mice,
pubmed-meshheading:16634846-Mice, Inbred C57BL,
pubmed-meshheading:16634846-Mice, Inbred DBA,
pubmed-meshheading:16634846-Motor Activity
|
pubmed:year |
2006
|
pubmed:articleTitle |
Topiramate does not affect the acquisition or expression of ethanol conditioned place preference in DBA/2J or C57BL/6J mice.
|
pubmed:affiliation |
Department of Behavioral Neuroscience and the Portland Alcohol Research Center, Oregon Health & Science University, Portland 97239-3098, USA. gremelc@ohsu.edu
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|