rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9518
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pubmed:dateCreated |
2006-4-24
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pubmed:abstractText |
Mild cognitive impairment is a syndrome defined as cognitive decline greater than expected for an individual's age and education level but that does not interfere notably with activities of daily life. Prevalence in population-based epidemiological studies ranges from 3% to 19% in adults older than 65 years. Some people with mild cognitive impairment seem to remain stable or return to normal over time, but more than half progress to dementia within 5 years. Mild cognitive impairment can thus be regarded as a risk state for dementia, and its identification could lead to secondary prevention by controlling risk factors such as systolic hypertension. The amnestic subtype of mild cognitive impairment has a high risk of progression to Alzheimer's disease, and it could constitute a prodromal stage of this disorder. Other definitions and subtypes of mild cognitive impairment need to be studied as potential prodromes of Alzheimer's disease and other types of dementia.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1474-547X
|
pubmed:author |
pubmed-author:BellevilleSylvieS,
pubmed-author:BennettDavidD,
pubmed-author:BrodatyHenryH,
pubmed-author:BroichKarlK,
pubmed-author:ChertkowHowardH,
pubmed-author:CummingsJeffrey LJL,
pubmed-author:FeldmanHowardH,
pubmed-author:GanguliMaryM,
pubmed-author:GauthierSergeS,
pubmed-author:HampelHaraldH,
pubmed-author:International Psychogeriatric Association Expert Conference on mild...,
pubmed-author:PetersenRonald CRC,
pubmed-author:ReisbergBarryB,
pubmed-author:RitchieKarenK,
pubmed-author:ScheltensPhilipP,
pubmed-author:TierneyMary CMC,
pubmed-author:WhitehousePeterP,
pubmed-author:WinbladBengtB,
pubmed-author:ZaudigMichaelM,
pubmed-author:de LeonMonyM
|
pubmed:issnType |
Electronic
|
pubmed:day |
15
|
pubmed:volume |
367
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1262-70
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
|
pubmed:year |
2006
|
pubmed:articleTitle |
Mild cognitive impairment.
|
pubmed:affiliation |
McGill Center for Studies in Aging, Douglas Hospital, Montréal, Quebec, Canada. serge.gauthier@mcgill.ca
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|