Linked Life Data

1662963

Source:http://linkedlifedata.com/resource/pubmed/id/1662963

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1992-2-26
pubmed:abstractText
With the aid of microiontophoretic techniques we tested the action of N-methyl-D-aspartate (NMDA) and an NMDA antagonist in the dendritic region of inner hair cell afferent fibers. In the majority of units tested NMDA enhanced the spontaneous firing rate. Furthermore, the activation of NMDA receptors triggered unusual depolarization patterns: (1) slow-frequency oscillation with a periodicity of about 3/min; (2) a fast oscillatory pattern of burst firing with a rhythmic interburst frequency of about 2/s. These findings provide evidence for NMDA receptor properties in the cochlea similar to those of analog channels in the central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0937-4477
pubmed:author
pubmed:issnType
Print
pubmed:volume
248
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
429-31
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
N-methyl-D-aspartate-induced oscillations in excitatory afferent neurotransmission in the guinea pig cochlea.
pubmed:affiliation
Division of Neurobiology, University of Berne, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't