Linked Life Data

16628513

Source:http://linkedlifedata.com/resource/pubmed/id/16628513

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-4-21
pubmed:abstractText
Marchiafava-Bignami disease is a rare disorder of an unknown aetiology that is marked by focal demyelinisation in the corpus callosum. Chronic alcohol abuse plays an important role in its development. Its course is unfavourable, although rare cases of clinical improvement confirmed in MRI have been reported. Until now, no case of Marchiafava-Bignami disease diagnosed intra vitam was so far described on the territory of Poland. The authors present such a case with favourable course. A 52-year-old male with chronic alcoholism was hospitalised due to altered consciousness which developed subacutely prior to admission. The first MRI scans yielded demyelinating lesions in the corpus callosum. The clinical and radiological findings were consistent with the diagnosis of Marchiafava-Bignami disease. Thiamine, vitamin B12, folic acid and amantadine were administered, which resulted in an improvement in both motor and cognitive functions. Control MRI scans revealed remyelinisation of the corpus callosum. Hence, this technique proved itself to be useful in monitoring the course of the disease.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-3843
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
156-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Reversible demyelinisation of corpus callosum in the course of Marchiafava-Bignami disease].
pubmed:affiliation
Klinika Neurologii CSK WAM, Wojskowy Instytut Medyczny, ul. Szaserów 128, 00-909 Warszawa 60. staszej@amwaw.edu.pl
pubmed:publicationType
Journal Article, English Abstract, Case Reports