Source:http://linkedlifedata.com/resource/pubmed/id/16626804
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2-3
|
| pubmed:dateCreated |
2006-5-15
|
| pubmed:abstractText |
A total of 50 Escherichia coli strains isolated in a Libyan hospital (20 from children with diarrhoea and 30 from healthy children) were investigated for their pathotypes and virulence traits. Altogether nine eae-positive (enteropathogenic E. coli, EPEC) and nine aggR-positive (entero-aggregative E. coli, EAEC) strains were identified. Significantly (P=0.001) more EPEC strains were identified from diarrhoeal patients (n=8) than from healthy controls (n=1), while six EAEC strains were identified from diarrhoeal and three from healthy children. Typical (eae(+), EAF(+), bfp(+)) EPEC strains (n=6) belonged to classical EPEC serogroups O55, O114, O127 and showed localized adherence on Hela cells. EAEC strains revealed genetic heterogeneity but uniformly adhered to HeLa cultures in an entero-aggregative adherence pattern. Antibiotic resistance frequently, characterized the strains. Sixty-eight percentage of the strains were resistant against at least one antibiotic and 30% harbored a class 1 integron independently of their clinical background. This is the first report from North Africa demonstrating the significance of EPEC and EAEC.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adhesins, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/AggR protein, E coli,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Escherichia coli Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/eaeA protein, E coli
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0147-9571
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
100-13
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:16626804-Adhesins, Bacterial,
pubmed-meshheading:16626804-Agglutination Tests,
pubmed-meshheading:16626804-Bacterial Adhesion,
pubmed-meshheading:16626804-Child, Preschool,
pubmed-meshheading:16626804-DNA, Bacterial,
pubmed-meshheading:16626804-Diarrhea,
pubmed-meshheading:16626804-Escherichia coli,
pubmed-meshheading:16626804-Escherichia coli Infections,
pubmed-meshheading:16626804-Escherichia coli Proteins,
pubmed-meshheading:16626804-HeLa Cells,
pubmed-meshheading:16626804-Humans,
pubmed-meshheading:16626804-Infant,
pubmed-meshheading:16626804-Libya,
pubmed-meshheading:16626804-Microbial Sensitivity Tests,
pubmed-meshheading:16626804-Polymerase Chain Reaction,
pubmed-meshheading:16626804-Sequence Analysis, DNA,
pubmed-meshheading:16626804-Serotyping,
pubmed-meshheading:16626804-Trans-Activators
|
| pubmed:articleTitle |
Phenotypic and genetic characterization of enteropathogenic Escherichia coli (EPEC) and entero-aggregative E. coli (EAEC) from diarrhoeal and non-diarrhoeal children in Libya.
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| pubmed:affiliation |
Veterinary Medical Research Institute of the Hungarian Academy of Sciences, Budapest, Hungary.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|