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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1992-2-19
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pubmed:abstractText |
1. In this study an acute anti-hypertensive effect of three anti-oxidant agents (vitamin C, thiopronine and glutathione) in hypertensive subjects and in both hypertensive and non-hypertensive diabetic patients is reported. 2. The anti-oxidants had no effect on blood pressure in healthy normal subjects at a dose of 6 mmol, but thiopronine and glutathione produced a significant hypotensive effect at a dose of 12 mmol. 3. These data suggest that anti-oxidants might have a dilatatory effect and that an imbalance of the nitric oxide-free radical interaction might facilitate the development of hypertension in humans.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0143-5221
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
739-42
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:1662579-Adult,
pubmed-meshheading:1662579-Antioxidants,
pubmed-meshheading:1662579-Ascorbic Acid,
pubmed-meshheading:1662579-Diabetes Mellitus, Type 1,
pubmed-meshheading:1662579-Double-Blind Method,
pubmed-meshheading:1662579-Drug Administration Schedule,
pubmed-meshheading:1662579-Female,
pubmed-meshheading:1662579-Glutathione,
pubmed-meshheading:1662579-Heart Rate,
pubmed-meshheading:1662579-Humans,
pubmed-meshheading:1662579-Hypertension,
pubmed-meshheading:1662579-Injections, Intravenous,
pubmed-meshheading:1662579-Male,
pubmed-meshheading:1662579-Middle Aged,
pubmed-meshheading:1662579-Tiopronin
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pubmed:year |
1991
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pubmed:articleTitle |
Anti-oxidants show an anti-hypertensive effect in diabetic and hypertensive subjects.
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pubmed:affiliation |
Cattedra di Diabetologia e Dietoterapia I Facoltà di Medicina, Università di Napoli, Italia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|