Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2006-4-18
pubmed:abstractText
Human defensin (HD) 5 and HD6, both Paneth cell alpha-defensins, contribute to the antimicrobial barrier against intestinal infection. We have previously demonstrated that levels of both HD5 and HD6 mRNA were reduced in adults living in urban Zambia, compared with those in adults living in London. The aim of the present study was to determine, during 2 years of follow-up, whether alpha-defensin expression in Zambian adults is related to susceptibility to diarrhea.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-10075954, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-10506557, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-10562592, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-10577203, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-10989307, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-11175848, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-11429515, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-11711773, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-11846026, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-11876715, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-12021776, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-12088856, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-12595421, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-12660734, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-12788978, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-1429669, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-14568394, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-14738460, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-15100456, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-4562265, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-5078330, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-6787548, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-7612236, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-8417977, http://linkedlifedata.com/resource/pubmed/commentcorrection/16619196-8977336
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
193
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1464-70
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed-meshheading:16619196-Adult, pubmed-meshheading:16619196-African Continental Ancestry Group, pubmed-meshheading:16619196-Cohort Studies, pubmed-meshheading:16619196-Diarrhea, pubmed-meshheading:16619196-Enterocolitis, Pseudomembranous, pubmed-meshheading:16619196-European Continental Ancestry Group, pubmed-meshheading:16619196-Female, pubmed-meshheading:16619196-Gene Expression Regulation, pubmed-meshheading:16619196-Genetic Predisposition to Disease, pubmed-meshheading:16619196-Genetics, Population, pubmed-meshheading:16619196-Humans, pubmed-meshheading:16619196-Incidence, pubmed-meshheading:16619196-Intestine, Small, pubmed-meshheading:16619196-Longitudinal Studies, pubmed-meshheading:16619196-Male, pubmed-meshheading:16619196-Middle Aged, pubmed-meshheading:16619196-RNA, Messenger, pubmed-meshheading:16619196-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:16619196-Zambia, pubmed-meshheading:16619196-alpha-Defensins
pubmed:year
2006
pubmed:articleTitle
Reduced gene expression of intestinal alpha-defensins predicts diarrhea in a cohort of African adults.
pubmed:affiliation
Centre for Adult and Paediatric Gastroenterology, Institute of Cell and Molecular Science, Barts and The London School of Medicine, Department of Infectious and Tropical Diseases, United Kingdom. guts@coppernet.zm
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't