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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
2006-4-18
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|
pubmed:abstractText |
Crohn's disease (CD) is a genetically complex disorder with strong familial aggregation. Pathogenesis appears to involve dysregulation of the immune response to endogenous bacteria. Anti-Escherichia coli outer membrane porin C (anti-OmpC) expression reflects an exaggerated response to commensal bacteria and occurs with higher frequency in CD. The aim of this study was to determine whether there is familial aggregation and genetic determination of anti-OmpC expression in CD families.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Apr
|
|
pubmed:issn |
0016-5085
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
130
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1078-85
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|
pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
|
|
pubmed:year |
2006
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|
pubmed:articleTitle |
Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease.
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|
pubmed:affiliation |
Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
