Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-6-20
pubmed:abstractText
The objective of the case-control study presented here was to examine the risk factors for macrolide-resistant Streptococcus pneumoniae. As part of a 44-center U.S. surveillance study, 1,817 unique isolates of S. pneumoniae were collected from November 2002 through April 2003. Seventy-five randomly selected macrolide-resistant isolates (cases) were each matched with one susceptible control. Macrolide use in the 6 weeks prior to sample collection was reported for seven cases and one control. The final conditional logistic regression model identified two statistically significant variables: a history of alcohol abuse was protective, while macrolide use in the 6 weeks prior to sample collection was a significant risk factor for macrolide-resistant S. pneumoniae. Macrolide resistance was associated with use of any antibiotic during the prior 6 weeks, and was most strongly associated with previous macrolide use.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0934-9723
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-9
pubmed:meshHeading
pubmed-meshheading:16612609-Adolescent, pubmed-meshheading:16612609-Adult, pubmed-meshheading:16612609-Aged, pubmed-meshheading:16612609-Aged, 80 and over, pubmed-meshheading:16612609-Anti-Bacterial Agents, pubmed-meshheading:16612609-Case-Control Studies, pubmed-meshheading:16612609-Child, pubmed-meshheading:16612609-Child, Preschool, pubmed-meshheading:16612609-Drug Resistance, Bacterial, pubmed-meshheading:16612609-Erythromycin, pubmed-meshheading:16612609-Female, pubmed-meshheading:16612609-Humans, pubmed-meshheading:16612609-Infant, pubmed-meshheading:16612609-Infant, Newborn, pubmed-meshheading:16612609-Macrolides, pubmed-meshheading:16612609-Male, pubmed-meshheading:16612609-Middle Aged, pubmed-meshheading:16612609-Pneumococcal Infections, pubmed-meshheading:16612609-Streptococcus pneumoniae
pubmed:year
2006
pubmed:articleTitle
Macrolide use identified as risk factor for macrolide-resistant Streptococcus pneumoniae in a 17-center case-control study.
pubmed:affiliation
Division of Medical Microbiology, Department of Pathology 265 MRC, University of Iowa, Iowa, IA, 52242, USA. susan-beekmann@uiowa.edu
pubmed:publicationType
Journal Article, Multicenter Study