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rdf:type |
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lifeskim:mentions |
umls-concept:C0017636,
umls-concept:C0034802,
umls-concept:C0851346,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1520166,
umls-concept:C1521871,
umls-concept:C1524063,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
7 Pt 1
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|
pubmed:dateCreated |
2006-4-12
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pubmed:abstractText |
The influence of epidermal growth factor receptor (EGFR) amplification on glioblastoma patient prognosis following definitive radiotherapy has been extensively investigated in clinical studies, and yet the relationship between EGFR status and radiation response remains unclear. The intent of the current study was to address this relationship using several EGFR-amplified glioblastoma xenografts in an orthotopic athymic mouse model.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BallmanKarla VKV,
pubmed-author:BrownPaul DPD,
pubmed-author:CarlsonBrett LBL,
pubmed-author:GianniniCaterinaC,
pubmed-author:GroganPatrickP,
pubmed-author:GuhaAbjahitA,
pubmed-author:JamesC DavidCD,
pubmed-author:KitangeGaspar JGJ,
pubmed-author:PanditaAjayA,
pubmed-author:SarkariaJann NJN,
pubmed-author:SchroederMark AMA
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
2264-71
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16609043-Adult,
pubmed-meshheading:16609043-Aged,
pubmed-meshheading:16609043-Animals,
pubmed-meshheading:16609043-Combined Modality Therapy,
pubmed-meshheading:16609043-Disease Models, Animal,
pubmed-meshheading:16609043-Dose-Response Relationship, Radiation,
pubmed-meshheading:16609043-Drug Screening Assays, Antitumor,
pubmed-meshheading:16609043-Female,
pubmed-meshheading:16609043-Gene Amplification,
pubmed-meshheading:16609043-Glioblastoma,
pubmed-meshheading:16609043-Humans,
pubmed-meshheading:16609043-Male,
pubmed-meshheading:16609043-Mice,
pubmed-meshheading:16609043-Mice, Nude,
pubmed-meshheading:16609043-Middle Aged,
pubmed-meshheading:16609043-Quinazolines,
pubmed-meshheading:16609043-Receptor, Epidermal Growth Factor,
pubmed-meshheading:16609043-Survival Rate,
pubmed-meshheading:16609043-Transplantation, Heterologous,
pubmed-meshheading:16609043-Xenograft Model Antitumor Assays
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pubmed:year |
2006
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pubmed:articleTitle |
Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.
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pubmed:affiliation |
Department of Radiation Oncology, Laboratory Medicine and Pathology, and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA. sarkaria.jann@mayo.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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