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pubmed-article:16608262pubmed:abstractTextWe report the in vivo targeting and imaging of tumor vasculature using arginine-glycine-aspartic acid (RGD) peptide-labeled quantum dots (QDs). Athymic nude mice bearing subcutaneous U87MG human glioblastoma tumors were administered QD705-RGD intravenously. The tumor fluorescence intensity reached maximum at 6 h postinjection with good contrast. The results reported here open up new perspectives for integrin-targeted near-infrared optical imaging and may aid in cancer detection and management including imaging-guided surgery.lld:pubmed
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pubmed-article:16608262pubmed:articleTitlePeptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects.lld:pubmed
pubmed-article:16608262pubmed:affiliationMolecular Imaging Program (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, USA.lld:pubmed
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pubmed-article:16608262pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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