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rdf:type |
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lifeskim:mentions |
umls-concept:C0003483,
umls-concept:C0012155,
umls-concept:C0033692,
umls-concept:C0205263,
umls-concept:C0221198,
umls-concept:C0221464,
umls-concept:C1257890,
umls-concept:C1704711,
umls-concept:C1705493,
umls-concept:C1879547,
umls-concept:C2756983
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pubmed:issue |
7
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pubmed:dateCreated |
2006-6-23
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pubmed:abstractText |
To study the distribution of group V secretory phospholipase A2 (sPLA2) in human and mouse lesions and compare its expression by human vascular cells, its activity toward lipoproteins, and the interaction with arterial proteoglycans (proteoglycans) with those of sPLA2-IIA. In addition, we also investigated the effect of a Western diet and lipopolysaccharide challenge on the aortic expression of these enzymes in mouse models.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD14,
http://linkedlifedata.com/resource/pubmed/chemical/Group II Phospholipases A2,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipases A,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipases A2,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1579-85
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16601231-Animals,
pubmed-meshheading:16601231-Antigens, CD14,
pubmed-meshheading:16601231-Aorta,
pubmed-meshheading:16601231-Arteries,
pubmed-meshheading:16601231-Atherosclerosis,
pubmed-meshheading:16601231-Blood,
pubmed-meshheading:16601231-Blood Vessels,
pubmed-meshheading:16601231-Carotid Artery Diseases,
pubmed-meshheading:16601231-Diet,
pubmed-meshheading:16601231-Drug Interactions,
pubmed-meshheading:16601231-Enzyme Induction,
pubmed-meshheading:16601231-Group II Phospholipases A2,
pubmed-meshheading:16601231-Humans,
pubmed-meshheading:16601231-Immunohistochemistry,
pubmed-meshheading:16601231-Isoenzymes,
pubmed-meshheading:16601231-Lipoproteins,
pubmed-meshheading:16601231-Macrophages,
pubmed-meshheading:16601231-Mice,
pubmed-meshheading:16601231-Phospholipases A,
pubmed-meshheading:16601231-Phospholipases A2,
pubmed-meshheading:16601231-Proteoglycans,
pubmed-meshheading:16601231-RNA, Messenger,
pubmed-meshheading:16601231-Recombinant Proteins,
pubmed-meshheading:16601231-Staining and Labeling
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pubmed:year |
2006
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pubmed:articleTitle |
Secretory phospholipase A2 group V: lesion distribution, activation by arterial proteoglycans, and induction in aorta by a Western diet.
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pubmed:affiliation |
AstraZeneca, R&D, Molecular Pharmacology, Mölndal S-431 83, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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