Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1590
pubmed:dateCreated
2006-4-7
pubmed:abstractText
The extreme polymorphism of the vertebrate major histocompatibility complex (Mhc) is famous for protecting hosts against constantly evolving pathogens. Mate choice is often evoked as a means of maintaining Mhc variability through avoidance of partners with similar Mhc alleles or preference for heterozygotes. Evidence for these two hypotheses mostly comes from studies on humans and laboratory mice. Here, we tested these hypotheses in a wild outbred population of house sparrows (Passer domesticus). Females were not more or less closely related to the males they paired with when considering neutral genetic variation. However, males failed to form breeding pairs when they had too few Mhc alleles and when they were too dissimilar from females at Mhc loci (i.e. had no common alleles). Furthermore, pairs did not form at random as Mhc diversity positively correlated in mating pairs. These results suggest that mate choice evolves in response to (i) benefits in terms of parasite resistance acquired from allelic diversity, and (ii) costs associated with the disruption of co-adapted genes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-10073943, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-1032893, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-1079575, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-11039932, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-11123629, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-11713527, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-11799397, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-12654829, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-14629387, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-14963312, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-14963619, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-14983018, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-15245418, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-15514149, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-15696759, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-16189664, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-1637966, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-1865924, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-3375818, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-3574474, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-4113158, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-7123238, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-8476562, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-8931360, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-9161019, http://linkedlifedata.com/resource/pubmed/commentcorrection/16600889-9597143
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0962-8452
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
273
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1111-6
pubmed:dateRevised
2010-9-16
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Complex Mhc-based mate choice in a wild passerine.
pubmed:affiliation
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Université Pierre et Marie Curie Paris 6, 7 quai St Bernard, bât. A 7ème étage, case 237, Paris 75252 Cedex 05, France. bonneaud@ucla.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't