Source:http://linkedlifedata.com/resource/pubmed/id/16599214
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2006-4-7
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pubmed:abstractText |
We present a moving-scatterer-sensitive optical Doppler tomography (MSS-ODT) technique for in vivo blood flow imaging in real time by using a spectral-domain optical coherence tomography system. In MSS-ODT the influence of stationary scatterers is suppressed by subtracting adjacent complex axial scans before calculating the Doppler frequency shift. We demonstrate that MSS-ODT is a useful technique for accurate determination of blood vessel size by imaging flow in a small capillary tube with a 75 microm inner diameter. The flow profile obtained with MSS-ODT yields a substantially more accurate tube diameter than that obtained with the conventional phase-resolved method, which underestimates the diameter by about 23%. We also demonstrate that MSS-ODT provides improved sensitivity over the conventional phase-resolved method for imaging in vivo blood flow in small vessels in a mouse ear.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0146-9592
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
927-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16599214-Algorithms,
pubmed-meshheading:16599214-Animals,
pubmed-meshheading:16599214-Blood Flow Velocity,
pubmed-meshheading:16599214-Computer Systems,
pubmed-meshheading:16599214-Ear,
pubmed-meshheading:16599214-Image Interpretation, Computer-Assisted,
pubmed-meshheading:16599214-Laser-Doppler Flowmetry,
pubmed-meshheading:16599214-Light,
pubmed-meshheading:16599214-Mice,
pubmed-meshheading:16599214-Scattering, Radiation,
pubmed-meshheading:16599214-Sensitivity and Specificity,
pubmed-meshheading:16599214-Tomography, Optical
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pubmed:year |
2006
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pubmed:articleTitle |
Real-time in vivo blood-flow imaging by moving-scatterer-sensitive spectral-domain optical Doppler tomography.
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pubmed:affiliation |
Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA. hwren@u.washington.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Evaluation Studies,
Research Support, N.I.H., Extramural
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