Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
2006-4-11
pubmed:abstractText
Driven by their beneficial effects on human metabolism, isoflavonoids have gained considerable importance reflected by an increased number of isoflavone-rich foods, food supplements and pharmaceutical products on the market, mainly derived from soy and red clover. While it is well known that the genuine isoflavone pattern will be altered during processing, data on aglycone stability are rare. Therefore, a thorough study into the thermal sensitivities of biochanin A, daidzein, formononetin, flavone, genistein, glycitein and isoflavone was performed. Samples were heated at 150 degrees C over a period of 7 h at three different pH values, and degradation of the aglycones was monitored by HPLC-DAD analyses. Therefrom, structure-related stability characteristics could be established. While virtually no decay was observed at pH 7.0 and 5.6, degradation was most prominent at pH 3. 1. Individual aglycone retention was further dependent on heating time with daidzein being the most labile compound after any time interval. Curve fitting of the data revealed first-order degradation kinetics for flavone and glycitein, while the remaining aglycones exhibited a sigmoidal degradation pattern.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1613-4125
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
373-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Thermal degradation kinetics of isoflavone aglycones from soy and red clover.
pubmed:affiliation
Institute of Food Technology, Plant Foodstuff Technology, Hohenheim University, Stuttgart, Germany. stintzin@uni-hohenheim.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't