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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1992-1-2
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pubmed:abstractText |
Epidemiologic studies revealed low mortality in hormone-dependent cancer in Japanese women and men consuming a traditional diet. We previously found that certain diphenolic food components, lignans and isoflavonoids, which are converted to biologically active hormone-like substances by intestinal microflora, may be cancer-protective agents. Therefore, we studied urinary excretion of these compounds (enterolactone, enterodiol, daidzein, equol, and O-desmethylangolensin) in 10 women and 9 men in a rural village south of Kyoto, Japan. The subjects consumed a typical low-fat diet with much rice and soy products, fish, and vegetables. An isotope-dilution gas chromatographic-mass spectrometric method was used for the assays. The urinary excretion of lignans was low but that of the isoflavonoids was very high. The excretion of isoflavonoids correlated with soybean-product intake. The low mortality in breast and prostate cancer of Japanese women and men, respectively, may be due to the high intake of soybean products.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Estrogens,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogens, Non-Steroidal,
http://linkedlifedata.com/resource/pubmed/chemical/Isoflavones,
http://linkedlifedata.com/resource/pubmed/chemical/Lignans,
http://linkedlifedata.com/resource/pubmed/chemical/Lignin,
http://linkedlifedata.com/resource/pubmed/chemical/Phytoestrogens,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Preparations
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1093-100
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1659780-Adult,
pubmed-meshheading:1659780-Aged,
pubmed-meshheading:1659780-Diet,
pubmed-meshheading:1659780-Estrogens,
pubmed-meshheading:1659780-Estrogens, Non-Steroidal,
pubmed-meshheading:1659780-Female,
pubmed-meshheading:1659780-Humans,
pubmed-meshheading:1659780-Isoflavones,
pubmed-meshheading:1659780-Japan,
pubmed-meshheading:1659780-Lignans,
pubmed-meshheading:1659780-Lignin,
pubmed-meshheading:1659780-Male,
pubmed-meshheading:1659780-Middle Aged,
pubmed-meshheading:1659780-Phytoestrogens,
pubmed-meshheading:1659780-Plant Preparations,
pubmed-meshheading:1659780-Urine
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pubmed:year |
1991
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pubmed:articleTitle |
Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet.
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pubmed:affiliation |
Department of Clinical Chemistry, University of Helsinki, Meilahti Hospital, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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