| pubmed-article:16596702 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0017638 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0555198 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0333051 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0872252 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C2827774 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0348080 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C2347946 | lld:lifeskim |
| pubmed-article:16596702 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:16596702 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:16596702 | pubmed:dateCreated | 2006-5-9 | lld:pubmed |
| pubmed-article:16596702 | pubmed:abstractText | The most common human brain tumours - gliomas - have poor prognosis with and without treatment. The current therapy conditions act sub-lethally and cannot effectively suppress the proliferation of glioma cells. Here we show differential protein expression patterns in surviving human malignant U87-MG glioma cells under clinically relevant chemo/radiotherapy. In parallel experiments, the cells underwent either irradiation (2 Gy, 200 KV X-ray) or chemotreatment with 30 microg/mL of temozolomide in the cultivation medium or combined chemo/radiation treatment. The cell cultures were treated during 5 days from day 4 until day 9 of growth. Modulated expression patterns of vimentin and RhoA GTPase indicate a potentially increasing grade of malignancy in treated cell fractions correlating well with extremely aggressive tumour phenotypes observed clinically at recidivation of treated malignant gliomas. | lld:pubmed |
| pubmed-article:16596702 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16596702 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16596702 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16596702 | pubmed:month | May | lld:pubmed |
| pubmed-article:16596702 | pubmed:issn | 1615-9853 | lld:pubmed |
| pubmed-article:16596702 | pubmed:author | pubmed-author:FountoulakisM... | lld:pubmed |
| pubmed-article:16596702 | pubmed:author | pubmed-author:Golubnitschaj... | lld:pubmed |
| pubmed-article:16596702 | pubmed:author | pubmed-author:FriedleinArno... | lld:pubmed |
| pubmed-article:16596702 | pubmed:author | pubmed-author:TrogDanielaD | lld:pubmed |
| pubmed-article:16596702 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16596702 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:16596702 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16596702 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16596702 | pubmed:pagination | 2924-30 | lld:pubmed |
| pubmed-article:16596702 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:meshHeading | pubmed-meshheading:16596702... | lld:pubmed |
| pubmed-article:16596702 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16596702 | pubmed:articleTitle | Is current therapy of malignant gliomas beneficial for patients? Proteomics evidence of shifts in glioma cells expression patterns under clinically relevant treatment conditions. | lld:pubmed |
| pubmed-article:16596702 | pubmed:affiliation | Department of Radiology, Division of Molecular/Experimental Radiology, Friedrich-Wilhelms-University of Bonn, Bonn, Germany. | lld:pubmed |
| pubmed-article:16596702 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16596702 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16596702 | lld:pubmed |
