Linked Life Data

16596450

Source:http://linkedlifedata.com/resource/pubmed/id/16596450

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-4-5
pubmed:abstractText
The mouse N-ethyl-N-nitrosourea (ENU) mutagenesis program at the Genomics Institute of the Novartis Research Foundation (GNF) uses MouseTRACS to analyze phenotype screens and manage animal husbandry. MouseTRACS is a Web-based laboratory informatics system that electronically records and organizes mouse colony operations, prints cage cards, tracks inventory, manages requests, and reports Institutional Animal Care and Use Committee (IACUC) protocol usage. For efficient phenotype screening, MouseTRACS identifies mutants, visualizes data, and maps mutations. It displays and integrates phenotype and genotype data using likelihood odds ratio (LOD) plots of genetic linkage between genotype and phenotype. More detailed mapping intervals show individual single nucleotide polymorphism (SNP) markers in the context of phenotype. In addition, dynamically generated pedigree diagrams and inventory reports linked to screening results summarize the inheritance pattern and the degree of penetrance. MouseTRACS displays screening data in tables and uses standard charts such as box plots, histograms, scatter plots, and customized charts looking at clustered mice or cross pedigree comparisons. In summary, MouseTRACS enables the efficient screening, analysis, and management of thousands of animals to find mutant mice and identify novel gene functions. MouseTRACS is available under an open source license at http://www.mousetracs.sourceforge.net.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-10781399, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-10886026, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-10886028, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-11567631, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-12547018, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-12724300, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-15018655, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-15064401, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-15170230, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-15534693, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-15691758, http://linkedlifedata.com/resource/pubmed/commentcorrection/16596450-16121255
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0938-8990
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
288-97
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Data and animal management software for large-scale phenotype screening.
pubmed:affiliation
Genomics Institute, Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA. mousetracs@users.sourceforge.net
pubmed:publicationType
Journal Article, Review