Linked Life Data

1659433

Source:http://linkedlifedata.com/resource/pubmed/id/1659433

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-12-30
pubmed:abstractText
The Om(2D)63 mutants were mutagenized by gamma-ray irradiation and DEB feeding. A total of nine revertants were recovered and characterized; eight revertants were homozygous-lethal expressing no appreciable abnormality in cuticular pattern and central nervous system, and all failed to complement the lethality with each other. Two of the eight expressed embryonic lethality and were associated with cytologically detectable deletions including the putative Om(2D) locus, while four were associated with rearrangements in a region distal to the insertion sites of the tom elements. No rearrangement was detected in the remaining two by Southern blot analysis. One of the nine revertants was homozygous-viable with wild-type eyes and was associated with a reciprocal translocation with the break points at 48B in 2R (Om(2D) locus) and 96A in 3R. Based on these data, it is concluded that interaction between the region comprised of a single complementation group of the recessive lethal and the inserted tom elements seems to be responsible for the Om(2D) mutant phenotype. In addition, two induced dominant enhancers specific to Om(2D)63 were identified; both mapped on chromosome 2.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-504X
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
387-97
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Genetic analysis of the Om(2D) locus in Drosophila ananassae.
pubmed:affiliation
Department of Biology, Faculty of Science, Tokyo Metropolitan University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't