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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-6-22
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pubmed:abstractText |
Celiac disease (CD) is a chronic disorder characterized by a pathological inflammatory response after exposure to gluten in genetically susceptible individuals. The HLA complex accounts for less than half of the genetic component of the disease, and additional genes must be implicated. Interleukin-10 (IL-10) is an important regulator of mucosal immunity, and several reports have described alterations of IL-10 levels in celiac patients. The IL-10 gene is located on chromosome 1, and its promoter carries several single nucleotide polymorphisms (SNPs) and microsatellites which have been associated to production levels. Our aim was to study the role of those polymorphisms in susceptibility to CD in our population.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-10226011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-10507725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-10773355,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-11196662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12198691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12229967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12370403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12458048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12618859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12738467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12911513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-12959221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-1431102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-14991925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15057267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15116066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15591503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15644122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15842590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-15979955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-16043989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-16048552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-16287542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-2205160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-9043871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-9689103,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16579847-9721152
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16579847-Case-Control Studies,
pubmed-meshheading:16579847-Celiac Disease,
pubmed-meshheading:16579847-Female,
pubmed-meshheading:16579847-Genetic Predisposition to Disease,
pubmed-meshheading:16579847-Haplotypes,
pubmed-meshheading:16579847-Heterozygote Detection,
pubmed-meshheading:16579847-Humans,
pubmed-meshheading:16579847-Interleukin-10,
pubmed-meshheading:16579847-Linkage Disequilibrium,
pubmed-meshheading:16579847-Male,
pubmed-meshheading:16579847-Microsatellite Repeats,
pubmed-meshheading:16579847-Polymorphism, Single Nucleotide,
pubmed-meshheading:16579847-Spain
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pubmed:year |
2006
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pubmed:articleTitle |
Interleukin-10 haplotypes in Celiac Disease in the Spanish population.
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pubmed:affiliation |
Department of Clinical Immunology, Hospital Clínico San Carlos, Madrid, Spain. connunez@usc.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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