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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-3-31
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pubmed:abstractText |
Linezolid is an oxazolidinone antibiotic that is increasingly used to treat drug-resistant, gram-positive pathogens. The mechanism of action is inhibition of bacterial protein synthesis. Optic and/or peripheral neuropathy and lactic acidosis are reported side effects, but the underlying pathophysiological mechanism has not been unravelled.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1537-6591
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pubmed:author |
pubmed-author:BoelaertJohan RJR,
pubmed-author:CosterRudy VanRV,
pubmed-author:De VrieseAn SAS,
pubmed-author:GrooteChantal Ceuterick-deCC,
pubmed-author:LoveringAndrewA,
pubmed-author:MartinJean-JacquesJJ,
pubmed-author:SenecaSaraS,
pubmed-author:SmetJoelJ,
pubmed-author:Van HauteLindsey LLL,
pubmed-author:VandecasteeleStefaanS,
pubmed-author:VanopdenboschLudo JLJ
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1111-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16575728-Acetamides,
pubmed-meshheading:16575728-Animals,
pubmed-meshheading:16575728-Anti-Infective Agents,
pubmed-meshheading:16575728-DNA, Mitochondrial,
pubmed-meshheading:16575728-Drug Therapy, Combination,
pubmed-meshheading:16575728-Female,
pubmed-meshheading:16575728-Humans,
pubmed-meshheading:16575728-Kidney,
pubmed-meshheading:16575728-Male,
pubmed-meshheading:16575728-Middle Aged,
pubmed-meshheading:16575728-Mitochondria,
pubmed-meshheading:16575728-Mitochondria, Liver,
pubmed-meshheading:16575728-Mitochondria, Muscle,
pubmed-meshheading:16575728-Oxazolidinones,
pubmed-meshheading:16575728-Protein Synthesis Inhibitors,
pubmed-meshheading:16575728-Rats,
pubmed-meshheading:16575728-Rats, Sprague-Dawley,
pubmed-meshheading:16575728-Rifampin,
pubmed-meshheading:16575728-Staphylococcal Infections
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pubmed:year |
2006
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pubmed:articleTitle |
Linezolid-induced inhibition of mitochondrial protein synthesis.
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pubmed:affiliation |
Department of Internal Medicine, AZ Sint-Jan AV, Bruges, Belgium. an.devriese@azbrugge.be
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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