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rdf:type |
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lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0009219,
umls-concept:C0014442,
umls-concept:C0025677,
umls-concept:C0178638,
umls-concept:C0332281,
umls-concept:C0600688,
umls-concept:C1337112,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C1882417
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pubmed:issue |
4
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pubmed:dateCreated |
2006-5-10
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pubmed:abstractText |
To determine associations of methotrexate (MTX) efficacy and toxicity with single-nucleotide polymorphisms (SNPs) in genes coding for folate pathway enzymes in patients with early rheumatoid arthritis (RA).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:AllaartCornelia FCF,
pubmed-author:BreedveldFerdinand CFC,
pubmed-author:DijkmansBen A CBA,
pubmed-author:Goekoop-RuitermanYvonne P MYP,
pubmed-author:GuchelaarHenk-JanHJ,
pubmed-author:HeijmansBas TBT,
pubmed-author:HuizingaTom W JTW,
pubmed-author:KerstensPit J S MPJ,
pubmed-author:SlagboomP ElinePE,
pubmed-author:WesselsJudith A MJA,
pubmed-author:de Vries-BouwstraJeska KJK,
pubmed-author:van ZebenDerkjenD
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1087-95
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16572443-Antirheumatic Agents,
pubmed-meshheading:16572443-Arthritis, Rheumatoid,
pubmed-meshheading:16572443-Female,
pubmed-meshheading:16572443-Humans,
pubmed-meshheading:16572443-Male,
pubmed-meshheading:16572443-Membrane Transport Proteins,
pubmed-meshheading:16572443-Methotrexate,
pubmed-meshheading:16572443-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16572443-Middle Aged,
pubmed-meshheading:16572443-Polymorphism, Single Nucleotide,
pubmed-meshheading:16572443-Reduced Folate Carrier Protein,
pubmed-meshheading:16572443-Tetrahydrofolate Dehydrogenase
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pubmed:year |
2006
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pubmed:articleTitle |
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
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pubmed:affiliation |
Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands. j.a.m.wessels@lumc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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