Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2006-4-12
pubmed:abstractText
The incidence of malaria in the East African highlands has increased since the end of the 1970s. The role of climate change in the exacerbation of the disease has been controversial, and the specific influence of rising temperature (warming) has been highly debated following a previous study reporting no evidence to support a trend in temperature. We revisit this result using the same temperature data, now updated to the present from 1950 to 2002 for four high-altitude sites in East Africa where malaria has become a serious public health problem. With both nonparametric and parametric statistical analyses, we find evidence for a significant warming trend at all sites. To assess the biological significance of this trend, we drive a dynamical model for the population dynamics of the mosquito vector with the temperature time series and the corresponding detrended versions. This approach suggests that the observed temperature changes would be significantly amplified by the mosquito population dynamics with a difference in the biological response at least 1 order of magnitude larger than that in the environmental variable. Our results emphasize the importance of considering not just the statistical significance of climate trends but also their biological implications with dynamical models.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-10322323, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-10756143, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-10810021, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-10974991, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-11297093, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-11499103, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-11832956, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-11859368, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-12478282, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-12482536, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-12498655, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-14641976, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-14983017, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-15189243, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-15605655, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-15847846, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-16292302, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-16595623, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-2231624, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-7898954, http://linkedlifedata.com/resource/pubmed/commentcorrection/16571662-9615495
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5829-34
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Malaria resurgence in the East African highlands: temperature trends revisited.
pubmed:affiliation
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA. pascual@umich.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural