Linked Life Data

1657112

Source:http://linkedlifedata.com/resource/pubmed/id/1657112

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-11-29
pubmed:abstractText
It has been claimed that the inner ear is generally resistant to the effects of radiotherapy schedules commonly used for treating head and neck cancer. A study was made of 28 patients previously irradiated for parotid pleomorphic adenoma to assess the effect on the audiovestibular apparatus. The dose most commonly used was 50 Gy in 15 daily fractions over 20 days and the median interval between radiotherapy and assessment was 14 years. Of 28 patients 15 had significant hearing deficit on the irradiated side on audiometry and this was predominantly sensorineural in type. In addition seven of these 15 patients had semicircular canal paresis. The reason for this morbidity may be arithmetic (total biological dose; dose per fraction) or geometric (upper extent; depth of target volume). Patients are now routinely warned of the possibility of late audiovestibular effects following radical radiotherapy to the parotid.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0936-6555
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-9
pubmed:dateRevised
2008-3-10
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Late audiovestibular consequences of radical radiotherapy to the parotid.
pubmed:affiliation
Department of ENT, Wythenshawe Hospital, Manchester, UK.
pubmed:publicationType
Journal Article