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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0018270,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0031727,
umls-concept:C0040132,
umls-concept:C0162508,
umls-concept:C0205088,
umls-concept:C0205263,
umls-concept:C0205464,
umls-concept:C0205618,
umls-concept:C0237477,
umls-concept:C0334227
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|
pubmed:issue |
3
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pubmed:dateCreated |
2006-3-30
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pubmed:abstractText |
The high radioresistance of anaplastic thyroid cancer (ATC) and cultured ATC cells stipulates for the means of increasing their radiosensitivity. It has been shown that c-Jun NH(2)-terminal kinase (JNK) activation is one of the manifestations of radiation response in ATC cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1050-7256
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
217-24
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16571083-Activating Transcription Factor 2,
pubmed-meshheading:16571083-Anthracenes,
pubmed-meshheading:16571083-Antineoplastic Agents,
pubmed-meshheading:16571083-Apoptosis,
pubmed-meshheading:16571083-Cell Aging,
pubmed-meshheading:16571083-Cell Line, Tumor,
pubmed-meshheading:16571083-Cell Proliferation,
pubmed-meshheading:16571083-Combined Modality Therapy,
pubmed-meshheading:16571083-DNA Repair,
pubmed-meshheading:16571083-Humans,
pubmed-meshheading:16571083-JNK Mitogen-Activated Protein Kinases,
pubmed-meshheading:16571083-Radiation-Sensitizing Agents,
pubmed-meshheading:16571083-Signal Transduction,
pubmed-meshheading:16571083-Thyroid Neoplasms
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pubmed:year |
2006
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pubmed:articleTitle |
Selective pharmacologic inhibition of c-Jun NH2-terminal kinase radiosensitizes thyroid anaplastic cancer cell lines via induction of terminal growth arrest.
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pubmed:affiliation |
Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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