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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2006-4-17
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pubmed:abstractText |
Hexavalent chromium has been extensively investigated regarding its mutagenicity and carcinogenicity; however, its mechanism for initiating and enhancing the development of lung cancer is still obscure. Biomarkers of exposure, effect or susceptibility are required for risk assessment and for epidemiologic research studies especially in occupational settings. Since the surfactant protein system (SP) is very important for normal lung function and for mediating local airway conditions and in the clearance of the upper respiratory tract from the occupational and environmental dusts, we hypothesize that SP genes may represent good candidates to study susceptibility for lung cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0271-3586
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2006 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
367-73
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pubmed:meshHeading |
pubmed-meshheading:16570259-Carcinogens, Environmental,
pubmed-meshheading:16570259-Case-Control Studies,
pubmed-meshheading:16570259-Chromium,
pubmed-meshheading:16570259-Confidence Intervals,
pubmed-meshheading:16570259-Genetic Predisposition to Disease,
pubmed-meshheading:16570259-Genotype,
pubmed-meshheading:16570259-Humans,
pubmed-meshheading:16570259-Japan,
pubmed-meshheading:16570259-Lung Neoplasms,
pubmed-meshheading:16570259-Metallurgy,
pubmed-meshheading:16570259-Middle Aged,
pubmed-meshheading:16570259-Occupational Diseases,
pubmed-meshheading:16570259-Occupational Exposure,
pubmed-meshheading:16570259-Polymerase Chain Reaction,
pubmed-meshheading:16570259-Protein Precursors,
pubmed-meshheading:16570259-Proteolipids
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pubmed:year |
2006
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pubmed:articleTitle |
Surfactant protein B gene variations and susceptibility to lung cancer in chromate workers.
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pubmed:affiliation |
Single-Molecule Bioanalysis Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Japan. ashraf-ewis@aist.go.jp
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pubmed:publicationType |
Journal Article
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