| pubmed-article:16570163 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16570163 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:16570163 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:16570163 | lifeskim:mentions | umls-concept:C0537270 | lld:lifeskim |
| pubmed-article:16570163 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:16570163 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:16570163 | pubmed:dateCreated | 2006-5-8 | lld:pubmed |
| pubmed-article:16570163 | pubmed:abstractText | Recombinant DNA technology is a useful tool that can be used to create insulin analogues with modified absorption kinetics to improve glycaemic control in patients with type 1 and type 2 diabetes. Among conventional insulin analogues, which are usually created by amino acid exchange, insulin detemir is the first analogue to be acylated with a fatty acid to enable reversible albumin binding. In this study we determined activation of the insulin receptor (IR)-signalling cascade by insulin detemir at the level of IR and IR substrate (Irs) phosphorylation, as well as downstream signalling elements such as phosphatidylinositol 3-kinase and Akt, and performed epidural EEG in vivo. | lld:pubmed |
| pubmed-article:16570163 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16570163 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16570163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16570163 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16570163 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:16570163 | pubmed:issn | 0012-186X | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:RussDD | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:FritschiMM | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:PreisslHH | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:TschritterOO | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:HennigeA MAM | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:HäringH-UHU | lld:pubmed |
| pubmed-article:16570163 | pubmed:author | pubmed-author:SartoriusTT | lld:pubmed |
| pubmed-article:16570163 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16570163 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:16570163 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16570163 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16570163 | pubmed:pagination | 1274-82 | lld:pubmed |
| pubmed-article:16570163 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:meshHeading | pubmed-meshheading:16570163... | lld:pubmed |
| pubmed-article:16570163 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16570163 | pubmed:articleTitle | Tissue selectivity of insulin detemir action in vivo. | lld:pubmed |
| pubmed-article:16570163 | pubmed:affiliation | Department of Internal Medicine IV, University of Tübingen, 72076 Tübingen, Germany. | lld:pubmed |
| pubmed-article:16570163 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16570163 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16570163 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16570163 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16570163 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16570163 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16570163 | lld:pubmed |
