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pubmed:abstractText |
Colorectal cancer (CRC), which has become especially prevalent in developed countries, is currently the third highest cause of cancer mortality in Taiwan. Mutation of the adenomatous polyposis coli (APC) gene, a tumour suppressor, is thought to be an early event in colorectal tumourigenesis. To date, however, no large-scale screening for APC gene variants in Chinese subjects has been performed. The present study was undertaken to identify APC gene variants that are significantly associated with the occurrence of CRC in Taiwanese subjects.
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pubmed:affiliation |
Institute of Medical Sciences, Buddhist Tzu Chi University: 703, Section 3, Chung-Yang Road, 970 Hualien, Taiwan. asdinap@yahoo.com.tw
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