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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-3-28
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pubmed:abstractText |
We have reported that peripheral lymphocyte reduction due to apoptosis is linked to the development of subsequent infectious complications in patients with severe acute pancreatitis and that Th1 (helper T cell type 1)/Th2 (helper T cell type 2) balance tends to cause Th1 suppression in experimental severe acute pancreatitis. It has been reported that interleukin (IL)-18 is a cytokine produced from Kupffer cells and activated macrophages, and that IL-18 acts on Th1 cells and in combination with IL-12 strongly induces production of interferon-gamma. However, the role of IL-18 in acute pancreatitis has not yet been fully understood.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0944-1174
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
158-65
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16568375-Acute Disease,
pubmed-meshheading:16568375-Blood Proteins,
pubmed-meshheading:16568375-CD4 Lymphocyte Count,
pubmed-meshheading:16568375-CD4-CD8 Ratio,
pubmed-meshheading:16568375-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16568375-Female,
pubmed-meshheading:16568375-Humans,
pubmed-meshheading:16568375-Hydrogen-Ion Concentration,
pubmed-meshheading:16568375-Interleukin-18,
pubmed-meshheading:16568375-Interleukin-6,
pubmed-meshheading:16568375-Interleukin-8,
pubmed-meshheading:16568375-Male,
pubmed-meshheading:16568375-Middle Aged,
pubmed-meshheading:16568375-Pancreatitis,
pubmed-meshheading:16568375-Severity of Illness Index,
pubmed-meshheading:16568375-T-Lymphocytes, Helper-Inducer
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pubmed:year |
2006
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pubmed:articleTitle |
Significant elevation of serum interleukin-18 levels in patients with acute pancreatitis.
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pubmed:affiliation |
Department of Gastroenterological Surgery, Kobe University Graduate School of Medical Sciences, Kobe 650-0017, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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