|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0034693,
umls-concept:C0038891,
umls-concept:C0040578,
umls-concept:C0040648,
umls-concept:C0185117,
umls-concept:C0392760,
umls-concept:C0521447,
umls-concept:C0521457,
umls-concept:C1171362,
umls-concept:C1513143,
umls-concept:C1947917,
umls-concept:C2911684
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|
pubmed:issue |
4
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pubmed:dateCreated |
2006-3-28
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|
pubmed:abstractText |
Mesenchymal nuclear transcription factors (MNTF) are involved in lung development and maturation and regulate surfactant protein (SP) expression. Prolonged (>2 weeks) fetal tracheal occlusion (TO) has been shown to accelerate lung growth and inhibit pulmonary surfactant synthesis. The effects of TO on SP expression and MNTF, however, have not been formally assessed. The objectives of this study were to evaluate the effects of short-term (3 days) TO on normal lung growth and protein expression of pulmonary MNTF involved in SP synthesis.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
1531-5037
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
41
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
774-80
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|
pubmed:meshHeading |
|
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pubmed:year |
2006
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|
pubmed:articleTitle |
Tracheal occlusion in fetal rats alters expression of mesenchymal nuclear transcription factors without affecting surfactant protein expression.
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|
pubmed:affiliation |
The Children's Institute for Surgical Science, Children's Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.
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pubmed:publicationType |
Journal Article
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