Source:http://linkedlifedata.com/resource/pubmed/id/16564661
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-7-24
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pubmed:abstractText |
We used tacrolimus to successfully treat a patient with childhood-onset oropharyngeal myasthenia gravis (MG). A girl (2 years, 5 months old) with oropharyngeal MG responded partially to treatment including pyridostigmine bromide, intravenous immunoglobulin, and prednisolone (2 mg/kg/day) for 7 weeks, but this resulted in worsening of her eye symptoms. By contrast, tacrolimus at 2 mg/day resulted in complete remission of the MG, which made it possible to reduce the dose of prednisolone. This is a rare report of the use of tacrolimus as an effective treatment for patients with intractable childhood-onset MG.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0387-7604
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pubmed:author |
pubmed-author:FukuyoNaomiN,
pubmed-author:HaginoyaKazuhiroK,
pubmed-author:IinumaKazuieK,
pubmed-author:IshitobiMamikoM,
pubmed-author:KakisakaYosukeY,
pubmed-author:KitamuraTaroT,
pubmed-author:SatoIkukoI,
pubmed-author:TogashiNorikoN,
pubmed-author:WakusawaKeisukeK,
pubmed-author:YokoyamaHiroyukiH,
pubmed-author:YoshiharaYasushiY
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
534-6
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pubmed:meshHeading |
pubmed-meshheading:16564661-Child, Preschool,
pubmed-meshheading:16564661-Female,
pubmed-meshheading:16564661-Humans,
pubmed-meshheading:16564661-Immunosuppressive Agents,
pubmed-meshheading:16564661-Myasthenia Gravis,
pubmed-meshheading:16564661-Tacrolimus,
pubmed-meshheading:16564661-Time Factors,
pubmed-meshheading:16564661-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Successful treatment of a 2-year-old girl with intractable myasthenia gravis using tacrolimus.
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pubmed:affiliation |
Department of Pediatrics, Tohoku University School of Medicine, 1-1 Seiryo-Machi, Sendai, Miyagi, Japan. kakisuke@mui.biglobe.ne.jp
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pubmed:publicationType |
Journal Article,
Case Reports
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