| pubmed-article:1655945 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0085112 | lld:lifeskim |
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| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0028630 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C1823153 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0441587 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0439097 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C2349976 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C1552644 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0442802 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C1547348 | lld:lifeskim |
| pubmed-article:1655945 | lifeskim:mentions | umls-concept:C0205144 | lld:lifeskim |
| pubmed-article:1655945 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1655945 | pubmed:dateCreated | 1991-11-1 | lld:pubmed |
| pubmed-article:1655945 | pubmed:abstractText | The severe combined immunodeficiency (SCID) mutation has been postulated to affect a V(D)J recombinase activity involved in coding joint formation. Analysis of 38 joints from 34 distinct sequences of normally rearranged T cell receptor (TCR) gamma and delta genes from adult, SCID thymocytes reveals coding joints with an increased number of P nucleotides. One-third of P sequences are greater than or equal to 4 nucleotides in length and P elements of up to 15 bases are observed. This suggests that the SCID defect deregulates P nucleotide addition. Consequently, essential V(D)J recombination intermediates may seldom be generated. | lld:pubmed |
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| pubmed-article:1655945 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:1655945 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1655945 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1655945 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1655945 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:1655945 | pubmed:author | pubmed-author:TuckerP WPW | lld:pubmed |
| pubmed-article:1655945 | pubmed:author | pubmed-author:KuzielW AWA | lld:pubmed |
| pubmed-article:1655945 | pubmed:author | pubmed-author:KienkerL JLJ | lld:pubmed |
| pubmed-article:1655945 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1655945 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:1655945 | pubmed:volume | 174 | lld:pubmed |
| pubmed-article:1655945 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1655945 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1655945 | pubmed:pagination | 769-73 | lld:pubmed |
| pubmed-article:1655945 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1655945 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1655945 | pubmed:articleTitle | T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion. | lld:pubmed |
| pubmed-article:1655945 | pubmed:affiliation | Department of Microbiology, University of Texas Southwestern Medical Center, Dallas 75235. | lld:pubmed |
| pubmed-article:1655945 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1655945 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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