Linked Life Data

1655454

Source:http://linkedlifedata.com/resource/pubmed/id/1655454

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1991-11-8
pubmed:abstractText
Murine cytomegalovirus infects a variety of organs after inoculation into adult male mice. We have established a model of myocarditis in which focal lesions from adjacent to virus-infected endothelial cells. The development of the myocarditis is mediated by CD4+ helper T cells. The lesions fail to develop when these cells are eliminated from the animal by administration of a specific monoclonal antibody. Alternatively, repletion of thymectomized, irradiated and bone-marrow reconstituted animals with CD4+ cells results in myocarditis. The evidence, although incomplete, suggests that a delayed hypersensitivity response is the pathogenetic mechanism involved.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0195-668X
pubmed:author
pubmed:issnType
Print
pubmed:volume
12 Suppl D
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Murine cytomegalovirus myocarditis.
pubmed:affiliation
Department of Pathology, University of Vermont College of Medicine, Burlington 05405.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.