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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-4-18
pubmed:abstractText
The estimation of chronological age in cadavers, human remains and in living human beings by various methods is discussed. These methods, which are based on the age dependent non-enzymatic changes of l-form amino acids to d-form amino acids, mainly aspartic acid, are among the most reliable and accurate methods to date. Most of these methods use gas chromatography (GC). In this review, results of aspartic acid racemization in dentin at different targets are discussed. In addition, pre-considerations and guidelines are given for the selection of dentin from teeth. A pilot project was run to evaluate the efficiency of high performance liquid chromatography (HPLC) coupled with fluorescence detection. New buffer conditions were found to obtain stable derivatives of aspartic acid enantiomers for the estimation of racemization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0379-0738
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
159 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S89-94
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Racemization of aspartic acid from human dentin in the estimation of chronological age.
pubmed:affiliation
Laboratory for Pharmaceutical Chemistry and Drug Analysis, Katholieke Universiteit Leuven, O&N2, Postbus 923, Herestraat 49, 3000 Leuven, Belgium.
pubmed:publicationType
Journal Article