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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-10-30
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pubmed:abstractText |
In a series of 131 patients we evaluated the effects of medical therapy with beta-Interferon cream in patients with cervical Human Papilloma Virus (HPV) infection, which in some cases, was associated with CIN. Treatment consisted of the direct daily application of 1,000,000 IU beta-Interferon cream to colposcopically positive areas over a period of 15 days. At intervals of 1, 6, 12 and 24 months following treatment, cytohistological tests were carried out to assess the effects of treatment. At the 24-month control, the overall percentage for regression was 79.57% of cases. Regression was observed in 58.33% of patients with cytohistological changes associated with HPV without atypia, and in 69.85% of patients with HPV with atypia (38.9% total regression). The regression pattern for CIN lesions was as follows: in CIN lesions, regression occurred in 85.36%, in CIN II in 84.20%, and 37.5% of CIN III cases showed total regression.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0390-6663
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1655314-Administration, Topical,
pubmed-meshheading:1655314-Adult,
pubmed-meshheading:1655314-Female,
pubmed-meshheading:1655314-Follow-Up Studies,
pubmed-meshheading:1655314-Humans,
pubmed-meshheading:1655314-Interferon-beta,
pubmed-meshheading:1655314-Middle Aged,
pubmed-meshheading:1655314-Papillomaviridae,
pubmed-meshheading:1655314-Remission Induction,
pubmed-meshheading:1655314-Tumor Virus Infections,
pubmed-meshheading:1655314-Uterine Cervical Diseases
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pubmed:year |
1991
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pubmed:articleTitle |
Beta-interferon topical treatment in low and high risk cervical lesions.
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pubmed:affiliation |
Service of Gynecologic Oncology and Cytodiagnostics, Institute of Gynecology, Padua University, Italy.
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pubmed:publicationType |
Journal Article
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