|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011306,
umls-concept:C0020792,
umls-concept:C0033684,
umls-concept:C0039194,
umls-concept:C0072595,
umls-concept:C0085358,
umls-concept:C0282580,
umls-concept:C0439855,
umls-concept:C0536940,
umls-concept:C1332714,
umls-concept:C1332717,
umls-concept:C1413244,
umls-concept:C1413787,
umls-concept:C1533691,
umls-concept:C1704858,
umls-concept:C1706438,
umls-concept:C1948023,
umls-concept:C2346689,
umls-concept:C2698600,
umls-concept:C2825965
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2006-3-22
|
|
pubmed:abstractText |
NY-ESO-1 belongs to a class of cancer/testis antigens and has been shown to be immunogenic in cancer patients. We synthesized a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein (CHP/ESO) and investigated the in vitro stimulation of CD8 and CD4 T cells from peripheral blood mononuclear cells in healthy donors with autologous CHP/ESO-loaded dendritic cells as antigen-presenting cells.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/CTAG1B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes, T-Lymphocyte,
http://linkedlifedata.com/resource/pubmed/chemical/Glucans,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Serological Subtypes,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR15 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/pullulan
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:GnjaticSachaS,
pubmed-author:HasegawaKoseiK,
pubmed-author:HiramatsuYujiY,
pubmed-author:KoizumiFumihitoF,
pubmed-author:MurphyRogerR,
pubmed-author:NakamuraHideoH,
pubmed-author:NakayamaEiichiE,
pubmed-author:NoguchiYujiY,
pubmed-author:OldLloyd JLJ,
pubmed-author:ShikuHiroshiH,
pubmed-author:ShimonoMichihideM,
pubmed-author:TanakaMotoyukiM,
pubmed-author:UenakaAkikoA
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1921-7
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:16551878-Amino Acid Sequence,
pubmed-meshheading:16551878-Antigen Presentation,
pubmed-meshheading:16551878-Antigens, Neoplasm,
pubmed-meshheading:16551878-Binding Sites,
pubmed-meshheading:16551878-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16551878-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16551878-Cell Line, Tumor,
pubmed-meshheading:16551878-Cholesterol,
pubmed-meshheading:16551878-Coculture Techniques,
pubmed-meshheading:16551878-Dendritic Cells,
pubmed-meshheading:16551878-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16551878-Epitopes, T-Lymphocyte,
pubmed-meshheading:16551878-Glucans,
pubmed-meshheading:16551878-HLA-DR Antigens,
pubmed-meshheading:16551878-HLA-DR Serological Subtypes,
pubmed-meshheading:16551878-Humans,
pubmed-meshheading:16551878-Hydrophobic and Hydrophilic Interactions,
pubmed-meshheading:16551878-Interferon-gamma,
pubmed-meshheading:16551878-Membrane Proteins,
pubmed-meshheading:16551878-Molecular Sequence Data
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
In vitro stimulation of CD8 and CD4 T cells by dendritic cells loaded with a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein: Identification of a new HLA-DR15-binding CD4 T-cell epitope.
|
|
pubmed:affiliation |
Department of Immunology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
