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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-3-22
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pubmed:abstractText |
Tie-2 is an endothelium-specific receptor tyrosine kinase known to play a key role in tumor angiogenesis. The present study explores the feasibility of immunotherapy of tumors by using a protein vaccine based on chicken Tie-2 as a model antigen to break the immune tolerance against Tie-2 in a cross-reaction between the xenogeneic homologous and self-Tie-2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:DengHong-XinHX,
pubmed-author:DingZhen-YuZY,
pubmed-author:FuChun-HuaCH,
pubmed-author:HeQiu-MingQM,
pubmed-author:KangBinB,
pubmed-author:LiJiongJ,
pubmed-author:LiuJi-YanJY,
pubmed-author:LuoYanY,
pubmed-author:MaoYong-QiuYQ,
pubmed-author:WeiYu-QuanYQ,
pubmed-author:WenYan-JunYJ,
pubmed-author:WuYangY,
pubmed-author:YeT XTX,
pubmed-author:YuJiangJ,
pubmed-author:ZhaoXiaX
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1813-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16551866-Animals,
pubmed-meshheading:16551866-Antigens, CD31,
pubmed-meshheading:16551866-Apoptosis,
pubmed-meshheading:16551866-Cancer Vaccines,
pubmed-meshheading:16551866-Cell Line,
pubmed-meshheading:16551866-Cell Line, Tumor,
pubmed-meshheading:16551866-Chickens,
pubmed-meshheading:16551866-Humans,
pubmed-meshheading:16551866-Immunoglobulins,
pubmed-meshheading:16551866-Immunohistochemistry,
pubmed-meshheading:16551866-Immunotherapy,
pubmed-meshheading:16551866-Melanoma, Experimental,
pubmed-meshheading:16551866-Mice,
pubmed-meshheading:16551866-Neoplasms, Experimental,
pubmed-meshheading:16551866-Neovascularization, Pathologic,
pubmed-meshheading:16551866-Receptor, TIE-2,
pubmed-meshheading:16551866-Survival Analysis,
pubmed-meshheading:16551866-T-Lymphocyte Subsets,
pubmed-meshheading:16551866-Time Factors,
pubmed-meshheading:16551866-Vaccines, Subunit
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pubmed:year |
2006
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pubmed:articleTitle |
Immunotherapy of tumors with protein vaccine based on chicken homologous Tie-2.
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pubmed:affiliation |
State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, Sichuan, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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