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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-3-22
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pubmed:abstractText |
Gemcitabine is a nucleoside analogue with activity against solid tumors. Gemcitabine metabolic inactivation is catalyzed by cytidine deaminase (CDA) or, after phosphorylation, by deoxycytidylate deaminase (DCTD). We set out to study the pharmacogenomics of CDA and DCTD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1794-803
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:16551864-African Americans,
pubmed-meshheading:16551864-Animals,
pubmed-meshheading:16551864-COS Cells,
pubmed-meshheading:16551864-Cercopithecus aethiops,
pubmed-meshheading:16551864-Cytidine Deaminase,
pubmed-meshheading:16551864-DCMP Deaminase,
pubmed-meshheading:16551864-Deoxycytidine,
pubmed-meshheading:16551864-European Continental Ancestry Group,
pubmed-meshheading:16551864-Genomics,
pubmed-meshheading:16551864-Haplotypes,
pubmed-meshheading:16551864-Humans,
pubmed-meshheading:16551864-Kinetics,
pubmed-meshheading:16551864-Linkage Disequilibrium,
pubmed-meshheading:16551864-Pharmacogenetics,
pubmed-meshheading:16551864-Polymorphism, Single Nucleotide,
pubmed-meshheading:16551864-Recombinant Proteins,
pubmed-meshheading:16551864-Sequence Analysis, DNA,
pubmed-meshheading:16551864-Transfection
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pubmed:year |
2006
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pubmed:articleTitle |
Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics.
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pubmed:affiliation |
Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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