Linked Life Data

16550720

Source:http://linkedlifedata.com/resource/pubmed/id/16550720

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10 Suppl
pubmed:dateCreated
2006-3-22
pubmed:abstractText
GH has a pivotal role in maintaining bone mass and metabolism both during childhood and in adult life. This effect depends on a complex interaction between circulating and peripherically produced GH and IGF-I. In vitro data and the use of genetically modified animals have greatly expanded the understanding of regulatory mechanisms underlying the well known skeletal changes featuring acromegalic disease. The present review focuses on the effects of GH excess on bone metabolism and mass in acromegalic patients with particular attention to the influence on bone metabolism as well as arthropathy of factors such as concomitant hypogonadism, gender, age of patients and therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0391-4097
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-5
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Acromegaly: effects on bone metabolism and mass.
pubmed:affiliation
Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy.
pubmed:publicationType
Journal Article, Review