Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-10-24
pubmed:abstractText
A longitudinal study was undertaken in a newly established specific pathogen-free (SPF) swine herd to determine the dynamics of rotavirus antigen shedding in a closed swine facility. Pregnant SPF gilts which populated the herd, and their offspring, were monitored weekly for three consecutive lactations. Fecal samples were assayed for the presence of group-specific viral antigen by a solid phase immunoassay (ELISA). Results indicate that in the week prior to farrow, 35% of samples from gilts/sows contained rotavirus antigen. During nursing, 37% of the gilts'/sows' fecal samples also contained virus antigen. Over the course of three farrowings, every gilt/sow in the herd excreted virus antigen. Virus antigen was present in 25% of the samples tested from nursing pigs and in 70% of the samples tested from pigs in the postnursing period; 95% of the litters excreted virus antigen either while nursing or postweaning. Seasonal incidence in virus antigen excretion was noted with proportionally more suckling pigs virus antigen-positive in summer and proportionally more sows/gilts positive during winter. Diarrhea occurred only rarely in the sampled population. Although piglets shed rotavirus subclinically, ELISA positive feces from piglets of each lactation caused severe disease when fed to neonatal gnotobiotic pigs. Electropherotyping of these passaged viruses indicated minor variation in RNA banding patterns over time.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0378-1135
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-29
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:1654666-Animals, pubmed-meshheading:1654666-Animals, Suckling, pubmed-meshheading:1654666-Antigens, Viral, pubmed-meshheading:1654666-Carrier State, pubmed-meshheading:1654666-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:1654666-Feces, pubmed-meshheading:1654666-Female, pubmed-meshheading:1654666-Germ-Free Life, pubmed-meshheading:1654666-Lactation, pubmed-meshheading:1654666-Longitudinal Studies, pubmed-meshheading:1654666-Pregnancy, pubmed-meshheading:1654666-Pregnancy Complications, Infectious, pubmed-meshheading:1654666-RNA, Viral, pubmed-meshheading:1654666-Rotavirus, pubmed-meshheading:1654666-Rotavirus Infections, pubmed-meshheading:1654666-Seasons, pubmed-meshheading:1654666-Specific Pathogen-Free Organisms, pubmed-meshheading:1654666-Swine, pubmed-meshheading:1654666-Swine Diseases, pubmed-meshheading:1654666-Weaning
pubmed:year
1991
pubmed:articleTitle
The shedding of group A rotavirus antigen in a newly established closed specific pathogen-free swine herd.
pubmed:affiliation
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana 61801.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't