| pubmed-article:16546322 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C0027627 | lld:lifeskim |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C0072461 | lld:lifeskim |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C0182953 | lld:lifeskim |
| pubmed-article:16546322 | lifeskim:mentions | umls-concept:C0084827 | lld:lifeskim |
| pubmed-article:16546322 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16546322 | pubmed:dateCreated | 2006-8-14 | lld:pubmed |
| pubmed-article:16546322 | pubmed:abstractText | The PEA3 group is composed of three highly conserved Ets transcription factors: Erm, Er81, and Pea3. These proteins regulate transcription of multiple genes, and their transactivating potential is affected by post-translational modifications. Among their target genes are several matrix metalloproteases (MMPs), which are enzymes degrading the extracellular matrix during normal remodelling events and cancer metastasis. In fact, PEA3-group genes are often over-expressed in different types of cancers that also over-express these MMPs and display a disseminating phenotype. Experimental regulation of the synthesis of PEA3 group members influences the metastatic process. This suggests that these factors play a key role in metastasis. | lld:pubmed |
| pubmed-article:16546322 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16546322 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16546322 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16546322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16546322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16546322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16546322 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16546322 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16546322 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:BaertJean-Luc... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:CoutteLaurent... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:MonteDidierD | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:Chotteau-Leli... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:FirlejVirgini... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:MauenSébastie... | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:DegernyCindyC | lld:pubmed |
| pubmed-article:16546322 | pubmed:author | pubmed-author:VerremanKathy... | lld:pubmed |
| pubmed-article:16546322 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16546322 | pubmed:volume | 1766 | lld:pubmed |
| pubmed-article:16546322 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16546322 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16546322 | pubmed:pagination | 79-87 | lld:pubmed |
| pubmed-article:16546322 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:meshHeading | pubmed-meshheading:16546322... | lld:pubmed |
| pubmed-article:16546322 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16546322 | pubmed:articleTitle | The Ets transcription factors of the PEA3 group: transcriptional regulators in metastasis. | lld:pubmed |
| pubmed-article:16546322 | pubmed:affiliation | UMR 8161, Institut de Biologie de Lille, CNRS/Université de Lille I/Université de Lille II/Institut Pasteur de Lille, BP 447, 1 rue Calmette, 59021 Lille Cedex, France. yvan.delaunoit@ibl.fr | lld:pubmed |
| pubmed-article:16546322 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16546322 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:16546322 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16546322 | lld:pubmed |
