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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0030705,
umls-concept:C0038952,
umls-concept:C0085862,
umls-concept:C0185117,
umls-concept:C1299583,
umls-concept:C1514422,
umls-concept:C1514474,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C2911684
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pubmed:issue |
2
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pubmed:dateCreated |
2006-6-1
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pubmed:abstractText |
In order to improve the survival of patients with a glioblastoma multiforme tumor (GBM), new therapeutic strategies must be developed. The use of a death inducing ligand such as TRAIL (TNF Related Apoptosis Inducing Ligand) seems a promising innovative therapy. The aim of this study was to quantify the expression of the death regulating receptors TRAIL-R1, TRAIL-R2 and TRAIL on primary GBM specimens and to correlate this expression with survival.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Regulatory Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, TNF-Related...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/TNF-Related Apoptosis-Inducing...,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF10A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF10B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TNFSF10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0167-594X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16544055-Apoptosis,
pubmed-meshheading:16544055-Apoptosis Regulatory Proteins,
pubmed-meshheading:16544055-Brain,
pubmed-meshheading:16544055-Brain Neoplasms,
pubmed-meshheading:16544055-Female,
pubmed-meshheading:16544055-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16544055-Glioblastoma,
pubmed-meshheading:16544055-Humans,
pubmed-meshheading:16544055-Immunohistochemistry,
pubmed-meshheading:16544055-Male,
pubmed-meshheading:16544055-Membrane Glycoproteins,
pubmed-meshheading:16544055-Middle Aged,
pubmed-meshheading:16544055-Prognosis,
pubmed-meshheading:16544055-RNA, Messenger,
pubmed-meshheading:16544055-Receptors, TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:16544055-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:16544055-Survival Analysis,
pubmed-meshheading:16544055-TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:16544055-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme.
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pubmed:affiliation |
Department of Neurosurgery, University Hospital Groningen, Groningen, The Netherlands. j.m.a.kuijlen@nchir.umcg.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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