Source:http://linkedlifedata.com/resource/pubmed/id/16541240
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-8-16
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pubmed:abstractText |
We examined transient receptor potential (TRP) V1 and TRPV2 expression in calcitonin gene-related peptide (CGRP) positive (+) primary sensory neurons projecting to the skin and skeletal muscles of the rat dorsum. Among the dorsal root ganglia at the levels from C2 to Th1, 34.9% of neurons projecting to the skin were positive for CGRP, and 32.6% or 21.6% of neurons projecting to the trapezius muscle or the longissimus muscle were positive for CGRP. Of the small CGRP+ neurons projecting to the skin, 53.5% were positive for TRPV1, 11.6% were positive for TRPV2. Of the small CGRP+ neurons projecting to the trapezius or the longissimus, 53.1 or 53.2% were positive for TRPV1, 8.8 or 8.3% were positive for TRPV2, respectively. In the periphery, 29.3% of CGRP+ nerve fibers were positive for TRPV1 in the skin, whereas 65.0 or 59.8% were positive in the trapezius or the longissimus. Therefore, the present study showed that the percentage of CGRP+ neurons projecting to the trapezius is higher than that to the longissimus, and that the co-localization percentage of CGRP and TRPV1 on the sensory nerves was also higher in the trapezius than in the longissimus and the skin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amidines,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Calcitonin Gene-Related...,
http://linkedlifedata.com/resource/pubmed/chemical/TRPV Cation Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Trpv1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Trpv2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/diamidino compound 253/50
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0948-6143
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-52
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pubmed:meshHeading |
pubmed-meshheading:16541240-Amidines,
pubmed-meshheading:16541240-Animals,
pubmed-meshheading:16541240-Fluorescent Dyes,
pubmed-meshheading:16541240-Ganglia, Spinal,
pubmed-meshheading:16541240-Immunohistochemistry,
pubmed-meshheading:16541240-Male,
pubmed-meshheading:16541240-Muscle, Skeletal,
pubmed-meshheading:16541240-Nerve Fibers,
pubmed-meshheading:16541240-Neurons, Afferent,
pubmed-meshheading:16541240-Rats,
pubmed-meshheading:16541240-Rats, Wistar,
pubmed-meshheading:16541240-Receptors, Calcitonin Gene-Related Peptide,
pubmed-meshheading:16541240-Skin,
pubmed-meshheading:16541240-TRPV Cation Channels,
pubmed-meshheading:16541240-Tissue Distribution
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pubmed:year |
2006
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pubmed:articleTitle |
Differential distribution of vanilloid receptors in the primary sensory neurons projecting to the dorsal skin and muscles.
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pubmed:affiliation |
Collage of Nursing, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan.
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pubmed:publicationType |
Journal Article
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