Linked Life Data

16540406

Source:http://linkedlifedata.com/resource/pubmed/id/16540406

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2006-3-16
pubmed:abstractText
Recently, the involvement of the inflammatory response in Alzheimer's disease (AD) has received considerable attention. The gene encoding for interleukin-6 (IL-6) is interesting since IL-6 has been reported not only to be involved in immune functions but also in AD. We investigated whether the IL-6-174 G/C polymorphism is associated with late onset AD (LOAD) in the Finnish subjects. The G allele was over-represented in ApoE4-LOAD patients but remained unimportant in all and in the ApoE E4 carriers. Interestingly, the G allele frequency was lower in our population in both AD patients and in controls compared to Southern European populations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0167-7063
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
155-61
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Interleukin-6 promoter polymorphism and late-onset Alzheimer's disease in the Finnish population.
pubmed:affiliation
Department of Medicine, Kuopio University Hospital and University of Kuopio, Kuopio, Finland. anne.koivisto@kuh.fi
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't