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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0018591,
umls-concept:C0034897,
umls-concept:C0205214,
umls-concept:C0439660,
umls-concept:C0936012,
umls-concept:C1140680,
umls-concept:C1511024,
umls-concept:C1516196,
umls-concept:C1556084,
umls-concept:C1705535,
umls-concept:C1742737
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pubmed:dateCreated |
2006-5-22
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pubmed:abstractText |
The 3398delAAAAG mutation in BRCA2 was recently found to recur in breast and/or ovarian cancer families from the French Canadian population of Quebec, a population that has genetic attributes consistent with a founder effect. To characterize the contribution of this mutation in this population, this study established the frequency of this mutation in breast and ovarian cancer cases unselected for family history of cancer, and determined if mutation carriers shared a common ancestry.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-10422801,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-10498392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-11170890,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-11254454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-11307153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-11453973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-11512557,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-14574645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-14615451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-15153996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-15382066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-7907678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-8635102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-8644702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-8673090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-8807330,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-8812419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-9497246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-9585613,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16539696-9792861
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
23
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16539696-Adult,
pubmed-meshheading:16539696-Aged,
pubmed-meshheading:16539696-Breast Neoplasms,
pubmed-meshheading:16539696-DNA Mutational Analysis,
pubmed-meshheading:16539696-Family Health,
pubmed-meshheading:16539696-Female,
pubmed-meshheading:16539696-Founder Effect,
pubmed-meshheading:16539696-France,
pubmed-meshheading:16539696-Gene Frequency,
pubmed-meshheading:16539696-Genes, BRCA2,
pubmed-meshheading:16539696-Haplotypes,
pubmed-meshheading:16539696-Heterozygote,
pubmed-meshheading:16539696-Humans,
pubmed-meshheading:16539696-Middle Aged,
pubmed-meshheading:16539696-Ovarian Neoplasms,
pubmed-meshheading:16539696-Quebec,
pubmed-meshheading:16539696-Sequence Deletion
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pubmed:year |
2006
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pubmed:articleTitle |
Haplotype analysis suggest common founders in carriers of the recurrent BRCA2 mutation, 3398delAAAAG, in French Canadian hereditary breast and/ovarian cancer families.
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pubmed:affiliation |
Department of Human Genetics, McGill University, Montreal, Canada. kathleen.klein@mail.mcgill.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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