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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-3-16
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pubmed:abstractText |
The use of nonsteroidal anti-inflammatory drugs (NSAIDs) and anticoagulants increases the risk of upper gastrointestinal bleeding. This article assesses its incidence in patients undergoing hip and knee arthroplasty. A single-center, retrospective study was conducted on 100 consecutive hip and 100 consecutive knee arthroplasties performed at the Victoria Infirmary, Glasgow, between 1998 and 2000. Sixty-three percent of patients were women with a mean age of 74. Fifty-four percent of patients received NSAIDs and all patients received anticoagulants perioperatively. Four and a half percent of patients had upper gastrointestinal bleeding postoperatively. We believe that the incidence of upper gastrointestinal bleeding as a complication is underestimated and recommend gastro-protective agents in the perioperative period for patients on NSAIDs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0147-7447
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
255-7
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pubmed:meshHeading |
pubmed-meshheading:16539204-Adult,
pubmed-meshheading:16539204-Aged,
pubmed-meshheading:16539204-Aged, 80 and over,
pubmed-meshheading:16539204-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:16539204-Anticoagulants,
pubmed-meshheading:16539204-Arthroplasty, Replacement, Hip,
pubmed-meshheading:16539204-Arthroplasty, Replacement, Knee,
pubmed-meshheading:16539204-Aspirin,
pubmed-meshheading:16539204-Barrett Esophagus,
pubmed-meshheading:16539204-Duodenal Ulcer,
pubmed-meshheading:16539204-Endoscopy, Gastrointestinal,
pubmed-meshheading:16539204-Female,
pubmed-meshheading:16539204-Gastrointestinal Hemorrhage,
pubmed-meshheading:16539204-Heparin, Low-Molecular-Weight,
pubmed-meshheading:16539204-Humans,
pubmed-meshheading:16539204-Length of Stay,
pubmed-meshheading:16539204-Male,
pubmed-meshheading:16539204-Middle Aged,
pubmed-meshheading:16539204-Postoperative Complications,
pubmed-meshheading:16539204-Proton Pumps,
pubmed-meshheading:16539204-Retrospective Studies,
pubmed-meshheading:16539204-Stomach Ulcer,
pubmed-meshheading:16539204-Venous Thrombosis
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pubmed:year |
2006
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pubmed:articleTitle |
Upper gastrointestinal bleeding after hip and knee arthroplasty.
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pubmed:affiliation |
Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom.
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pubmed:publicationType |
Journal Article
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